Review: clomipramine is more effective than SSRIs for paediatric obsessive compulsive disorder

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منابع مشابه

Review: clomipramine is more effective than SSRIs for paediatric obsessive compulsive disorder.

Geller DA, Biederman J, Stewart SE, et al. Which SSRI? A meta-analysis of pharmacotherapy trials in pediatric obsessive-compulsive disorder. Am J Psychiatry 2003;160:1919–28. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...

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Review: in obsessive-compulsive disorder, clomipramine may be more effective than selective serotonin reuptake inhibitors after controlling for other factors.

Study selection Studies were eligible if they were randomised, doubleblind parallel trials of at least 8 weeks duration; used the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) to assess the efficacy of clomipramine or selective serotonin reuptake inhibitors for obsessive-compulsive disorder, and included point estimates, standard deviations or calculable data. The authors included 25 trials.

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Clomipramine in Resistant Obsessive Compulsive Disorder

Twelve subjects with a diagnosis of Obsessive Compulsive Disorder who had not shown response to amitryptiline and imipramine/behaviour therapy underwent a cross over double blind trial with clomipramine and nortryptiline. Subjects who had earlier not shown response to the other drugs did not show response to clomipramine. The implications of these findings for clinical management are discussed.

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Intravenous Clomipramine for Treatment-Resistant Obsessive-Compulsive Disorder

BACKGROUND This open trial was conducted to evaluate the effectiveness of intravenous clomipramine (CMI) in refractory obsessive-compulsive disorder (OCD). METHODS Thirty OCD poor responders to previous multiple trials of anti-obsessive medications were selected and admitted to the hospital. Severity of the illness and response to treatment were primarily assessed by the Yale-Brown Obsessive ...

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Neurocognitive function in paediatric obsessive-compulsive disorder.

OBJECTIVES The small body of neuropsychological research in paediatric obsessive-compulsive disorder (OCD) yields inconsistent results. A recent meta-analysis found small effect sizes, concluding that paediatric OCD may not be associated with cognitive impairments, stressing the need for more research. We investigated neuropsychological performance in a large sample of youths with OCD, while as...

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ژورنال

عنوان ژورنال: Evidence-Based Mental Health

سال: 2004

ISSN: 1362-0347

DOI: 10.1136/ebmh.7.2.50